1.What is hypertensive nephropathy?
original hypertensive cause hypertensive nephropathy and make benign arteriolar nephrosclerosis and malignant arteriolar nephrosclerosis, and accompanied by the corresponding clinical manifestations of disease.
2What’s the pathogenesis of hypertensive nephropathy?
kidney is a organ than surround by blood capillary, it used to Filtering body endotoxin, prevent Proteins, blood cells and other substances leaking blood vessels. high blood pressure make the pressure of Intravascular blood increase, it cause protein leaking, if protein leaking can damage kidney strainer system, and lead to vicious circle, long time damage can’t be repaired, kidney Compensatory increase until failure. What’s the clinical manifestation of hypertensive nephropathy?
1) severe edema:
edema often is the first symptoms, it appear the whole body edema, if take finger press it has hollow, severe patients have hydrothorax, ascites. it may cause hard breath Umbilical hernia or inguinal hernia, height edema often appear less urine, high blood pressure, mild azotemia.
2)large number proteinuria
large number of proteinuria is the main symptom of nephrotic syndrome, urine prote often determine the nature is ++~++++，everyday adult urine protein discharge≥3．5g/d, most is selectivity proteinuria.
plasma proteins reduce , serum albumin < 30 g/L, even less than 10 g/L
blood cholesterol and triglyceride are significantly increase
In clinic, according to condition and test divide hypertensive nephropathy into several stages.
1) microalbuminuria: characterized by abnormal urine albumin excretion rate. Normal renal function, routine urine protein is negative.
2) clinical proteinuria: routine urine protein is positive, 24 h urinary protein quantitative > 0.5 g is the characteristics, normal renal function.
3) renal insufficiency: the characteristics is Ccr drop, SCr increase, divide into no dialysis period and dialysis period (uremia period).V 4) no dialysis period: Ccr is 40～10ml/min，133μmol/L < Scr < 707μmol/L
5) dialysis period (uremia period): Ccr < 10ml/min．Scr>707μmol/L
The treatment of hypertensive nephropathy
1.at early stage, mild hypertension and routine urine is near normal can take non-drug therapy, keep good emotion, lose weight, limit salt intake, quit drink, and take some exercise.
2. antihypertensive drugs
(2) beta blockers;
(3) Calcium channel blockers;
Read more>>Related articles
Even hypertension is common in our daily life, but it has big perniciousness. Meanwhile, it also can...Read More>>
In the word, hypertension is a common disease, no matter male or female, old or young, many people s...Read More>>
Never blind lowering blood pressure: people should figure out the basic reason of blood pressure ris...Read More>>
For diet, patient should control energy and salt intake, reduce fat and cholesterol intake, control ...Read More>>
Fatigue is a common symptom of hypertensive nephropathy, which is mainly induced by anemia. Kidney h...Read More>>
At present, people often intake high fat, high protein and high heat diet, it make hypertensive neph...Read More>>
If people’s age between 40-50 years old and hypertension medical history is more than five years, n...Read More>>
Mistake 1: obese people will have high blood pressure
Obesity is an important factor of high blood ...Read More>>
Nitin (pseudonym) is a 23 years old student, he ha...Read More>>
On December 25th, there is a party hold in our hos...Read More>>
Nilasha is a 10 years old girl from Bangladesh. Sh...Read More>>
Abdullahis a boy from Saudi Arabia. He is sufferin...Read More>>
Olufemi is a male from Nigeria. He is suffering fr...Read More>>